eNOS Promoter Activation by Red Wine Polyphenols: an Interaction Study
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چکیده
منابع مشابه
In vitro antioxidant activities of three red wine polyphenols and their mixtures: an interaction study.
The well-known antioxidant activity of red wine is explained mostly by its polyphenols content, where the final effect is based on the wine components' interaction. The aim of our work was the study of the interaction of three red wine polyphenols--quercetin, resveratrol and caffeic acid--alone and in their equimolar binary and ternary mixtures in different antioxidant/scavenging assays (inhibi...
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Conventional cancer therapies, the second leading cause of death worldwide, result in serious side effects and, at best, merely extend the patient's lifespan by a few years. Searching for effective prevention is of high priority in both basic and clinical sciences. In recent decades natural products have been considered to be an important source of cancer chemopreventive agents. Red wine polyph...
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It became evident in the present study that carbon tetrachloride (CCl(4)), in addition to its known liver and renal toxicity, causes serious damage to endothelial cells. The preventive effect of red wine on cardiovascular diseases has been documented in a number of human population studies as well as in animal experimental models. In this study, the endothelium protective effect of polyphenolic...
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The aim of the present study was to investigate the mechanism of vasorelaxant responses induced by red wine polyphenolic compounds (Provinol). Rings of rat femoral artery with or without functional endothelium were set up in a myograph for isometric recording and precontracted with phenylephrine (10(-5) M). Provinol in cumulative doses (10(-9) to 10(-3) mg/ml) elicited endothelium- and dose-dep...
متن کاملOlive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals.
OBJECTIVE Epidemiology suggests that Mediterranean diets are associated with reduced risk of cardiovascular disease. Because monocyte adhesion to the endothelium is crucial in early atherogenesis, we evaluated whether typical olive oil and red wine polyphenols affect endothelial-leukocyte adhesion molecule expression and monocyte adhesion. METHODS AND RESULTS Phytochemicals in olive oil and r...
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ژورنال
عنوان ژورنال: Acta Facultatis Pharmaceuticae Universitatis Comenianae
سال: 2013
ISSN: 0301-2298
DOI: 10.2478/afpuc-2013-0013